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8B, C) in the orthotopical xenograft model (Supplementary Fig

Intranasal delivery using a lung-tropic adeno-associated virus 9 vector to prime and chemokine pull (CXCL11) effectively induced SARS-CoV-2-specific lung-resident T cells and offered better protection against SARS-CoV-2 in mice [168] (Table 2)

This effect is accomplished through the selective inhibition of the anti-apoptotic protein Bcl-2 expression, while significantly upregulating the activity levels of the pro-apoptotic protein Bax and the apoptotic execution factor caspase-9, thereby promoting apoptosis (Safarbalou et al., 2024)

Hepatocytes are supported by a number of other cell types, which account for 40% of the liver cell mass