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In cases where this process is disrupted, such as bacterial infection, neutrophil accumulation persists, leading to elevated levels of elastase and matrix metalloproteinases (MMPs) that degrade the extracellular matrix (ECM) and impair tissue repair [27]

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Excessive neuronal loss resulting from increased apoptosis can lead to shrinkage of critical brain regions involved in mood regulation, including the hippocampus and prefrontal cortex

We examined sex- and gender-related differences in participants of a national CVT randomized trial and registry