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In addition, compulsivity trait (OCI) was also related to changes in SMA Glu levels, both in healthy volunteers and participants with OCD, consistent with the notion of a transdiagnostic dimension characterising compulsive behaviour related to connectivity of frontal regions 2

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Am J Clin Exp Immunol (2018) 7:506

In a phase 2 study, comparing the results of the empagliflozin arm to the control arm showed a significant improvement in the electrophysiological studies and a significant decrease in the pain score and the mean serum levels of neuron-specific enolase and malondialdehyde in patients with DPN