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F., Santacruz, E., Luque-Ramrez, M

3.4 Alleviate excitotoxicity of glutamic acid in CNS Following an ischemic stroke, hypoxia in the central nervous system disrupts ATP-dependent ion transport and neurotransmitter reuptake, leading to the excessive release and extracellular accumulation of glutamate

This finding correlated with higher neural cell numbers and GCL-localised VEGF levels compared to WT litter mate control mice indicating an effect or adaption that occurs during retinal development 34