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On one hand, STING activation has been shown to promote the differentiation of nave CD4 T cells into Th1 and Th9 cells and enhance the production of effector cytokines such as IFN- and IL-9, thereby augmenting CD4 T cell effector functions [229]

Laminin Targeting of a Peripheral Nerve-Highlighting Peptide Enables Degenerated Nerve Visualization

258 Its inhibition of 3T3-L1 adipocyte differentiation is an indirect function, involving the suppression of PPAR transcriptional activity and a decrease in reactive oxygen species (ROS) levels during early adipogenesis

In addition to mitochondrial pathways, gene therapy is also focusing on neuroprotection and the preservation of RGCs by preventing their degeneration