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Although PZQ is a safe and effective drug against all forms of schistosomiasis 9 , its extensive use in MDA programs raises concerns about resistance 10

Mol Genet Metab 136:268273

Macrophages, as the primary source of inflammatory mediators, can secrete pro-inflammatory factors such as TNF- to facilitate IR formation by augmenting serine phosphorylation of insulin receptor substrate-1 (109)