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Pralmorelin is known for producing a strong growth hormone release response through ghrelin receptor activation

5 Whitehead N, Reyner F, Lindenbaum J

C57BL6/J WT (Gstp1/2 +/+ ) mice and Gstp1/2 knockout (Gstp1/2 / ) mice in C57BL6/J background were provided by Professor Roland Wolf and Cancer Research UK

Interestingly, the process can be reversed, as old mice exposed to a youthful systemic environment via heterochronic parabiosis recover a remyelination potential similar to that of young mice (Ruckh et al., 2012)