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Results: GHK-Cu treatment attenuated the CS-induced emphysematous changes and partially reversed the matrix metalloprotein -9 (MMP-9)/tissue inhibitor of metalloproteinases-1 (TIMP-1) imbalance in the lung tissue

Targeting mitochondrial ROS production through mitochondrial-targeted antioxidants like MitoQ, and enhancing antioxidant defenses through NRF2 activators, are promising strategies for vitiligo treatment (135)

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Cytotoxic CD8+ T-lymphocytes (CTL) are considered the major defense mechanism against tumor cells, hence T-cell abundance is a decisive and crucial prognostic factor for immunotherapy and chemotherapy response, particularly at the early tumor initiation stage, where an increased activity of T cells has been reported (9)