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Emerging pharmacotherapies for obesity: A systematic review

Storage Instructions Store mixed semaglutide in a refrigerator (28C or 3646F) Do not freeze Use within 28 days of reconstitution Always use sterile syringes for each dose withdrawal Properly mixing semaglutide with bacteriostatic water ensures both safety and efficacy

Higher doses produce increased incidence and severity of gastrointestinal symptoms, which explains why clinical protocols use gradual dose escalation starting at 0.25 mg weekly and incrementally increasing every 4 weeks