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5A-1MQ-treated mice switched from WD to LD were particularly distinct from mice in the other groups when k-means clustering was applied to the ASV relative abundance data

The 2024 fusion-peptide work exists precisely because researchers recognized that native DSIPs delivery to the brain is the bottleneck, and engineered around it by fusing DSIP to a blood-brain-barrier-crossing TAT transduction domain (sequence GGGGYGRKKRRQRRR) via flexible GGGGS linkers, expressed and secreted from Pichia pastoris

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The detrimental consequence of muscle transection outweighs crush injury, and after quadriceps muscle transection more VEGF and CD34 positive elements were present than after blunt trauma