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(PubMed) Cantorna MT, Woodward WD, Hayes CE, DeLuca HF

Moreover, addition of hyaluronic acid to the azelaic acid nanoemulsions efficiently reduce melanin synthesis through the enhanced melanocyte-nanoemulsion interactions ( Based on the results of a previous in vitro study, hydroquinone 4% microemulsions showed higher amounts of drug release, higher drug stability, and reduced skin irritation and skin layer disturbance in comparison to the conventional hydroquinone cream (stnda Okur et al., 2019)