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This presents a potential therapeutic target for attenuating sorafenib- and ponatinib-induced cardiotoxicity (Figure 1)

Compared to the nonsignificant logRR of 0.36 for side effects from the primary analysis, iterative removal of one study at a time resulted in logRR values ranging from 0.29 to 0.42, with all p-values 0.18

Dansyl chloride Dansyl chloride or 5-(dimethylamino)naphthalene-1-sulfonyl chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-greenfluorescent sulfonamide adducts