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Current Opinion in Colloid & Interface Science

In conclusion, metformin has demonstrated many therapeutic advantages in the treatment of patients with PCOS across multiple life stages, including puberty, pregnancy, and long-term health management

Therefore, the increased expression of miR-153-3p inhibited neuronal cell apoptosis and decreased inflammation in microglia by blocking the NF-B/iNOS/COX2 pathway while enhancing activation of the Nrf2/HO-1 signaling cascade