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Not sure if you know this but it's worth mentioning that if you have any neurological symptoms when you were diagnosed, the B12 regime (according to all guidelines) is six loading doses of 1mg B12 and then 1mg injections every other day until no further improvement (for some people this takes many months)

The role of oxidative stress in the pathogenesis of COPD: implications for therapy

One such enzyme is cystathionine beta-synthase (CBS), which catalyzes the first and most important (rate-limiting) step in trans-sulfuration from homocysteine to cystathionine

Glutathione is a naturally occurring antioxidant found in every cell of the body