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Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells

Basu S, Banerjee D, Chandra S, Chakrabarti A

The gut microbiota regulates the metabolism and side effects of irinotecan (CPT-11), a topoisomerase inhibitor prodrug of SN-38 that is frequently used to treat colorectal cancer (Wallace et al., 2018)