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J Cell Mol medicine

SHMT enzymes play a pivotal role in cellular one-carbon metabolism by catalyzing the reversible conversion of glycine to L-serine and coupled to the interconversion of 5,10-methylenetetrahydrofolate (5,10-CH2-THF) and tetrahydrofolate (THF)

Retrieved August 13, 2021, from Nowak, I., Byliska, A., Wilczyska, K., Winiewski, A., Malinowski, A., Wilczyski, J

Consistently, in vitro experiments using miRNA mimics and inhibitors evidenced that miR-26a overexpression determined a reduction in cell proliferation whereas miRNA inhibition increased cell proliferation