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10.1016/j.ejmech.2019.07.062 176 ZhangJ.ZhenY-f.Pu-Bu-Ci-RenSongL-g.KongW-n.ShaoT-m.et al (2013)

Kumar H, Kawai T, Akira S

1,2 Atherosclerosis is generally caused by a combination of endothelial dysfunction, inflammation, and oxidative stress, which may be induced by a range of conditions such as smoking, unhealthy lifestyle, abnormal lipid levels, insulin resistance, obesity, and high blood pressure

In fact, its been found that B12 supplements taken orally are just as effective as intramuscular shots in overcoming states of deficiency when you take up to 1,000 micrograms a day