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Vitamin B12, also called cyanocobalamin, is a water soluble vitamin that is often supplemented in cats with certain health conditions, especially of the GI tract

These findings collectively identify the FOXO4-p53 axis as a potential pharmacological target in brain aging and highlight senolytic therapy as a promising strategy for altering diseases to postpone or reverse age-related cognitive decline

The obesity trial showed weight reductions of up to 14.7% at 36 weeks with the 45 mg dose, while the diabetes trial demonstrated HbA1c reductions of up to 2.1 percentage points and weight loss of up to 10.1 kg at 26 weeks

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