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A similar method was used for the MDA quantification, assessed also by HPLC Chromsystems (Grfelfing/Mnchen, Germany)

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Firstly, the Xc system (solute carrier family 7 member 11 and family 3 member 2 (SLC7A11 and SLC3A2)) is responsible for taking up cystine to generate the substrate cysteine for the synthesis of GSH and is also involved in the formation of the GPX4 catalytic unit