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First, we established hiPSCs cell lines (RC hiPSCs) with MFN2 overexpressing and knockdown separately (Fig

Compound 1: Retatrutide Research Findings Molecular Structural studies of triple agonism at GLP-1R, GIPR, and GCGR via cryo-EM

Finally, we found a similar decrease in survival when treating CCNE1-driven cells with PARP inhibitors that have less PARP-trapping activity than olaparib (Extended Data Fig