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Peripheral Presynaptic In addition to its dominant central action, clonidine stimulates peripheral presynaptic 2 Feedback: 2 -autoreceptors located on sympathetic postganglionic nerve terminals

Yong Y, Yan L, Wei J et al

In contrast, it has been observed that older people have a lower risk for the rejection of heart transplants [139] which indicates that an increased immunosuppressive state improves their transplantation tolerance