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Rating: 4.7731 (27 reviews)

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Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors

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Studies have also showed that high-dose folic acid supplementation (up to 4000g/day) significantly lowered tHcy concentrations for all MTHFR C677T genotypes and the effect size of tHcy reduction in the TT genotype was estimated to be 2.4-fold compared with that in the CC genotype