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Washing State University has stated NRF2 to be: "The most extraordinary therapeutic and most extraordinary preventive breakthrough in the history of medicine." Additionally, they stated the following: "Nrf2 is argued to be both lifespan and healthspan extending." "Nrf2 is likely to be the most important health promoting approach into the foreseeable future." - Source

Acosta, C.R

349 Single large-scale mtDNA deletions exhibit phenotypic heterogeneity and contribute to a spectrum of diseases, including Pearson syndrome, Kearns-Sayre syndrome, and PEO