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higher scores represent more active disease), an endoscopic subscore of 2, colonic involvement of 15 cm, and a confirmed diagnosis of ulcerative colitis for 3 months

The IRB waived the need for written informed consent when it was previously obtained at entry into the SHAVE cohort

As miR-194-3P is responsible for progesterone resistance [119] and apigenin can modulate progesterone receptor [175], hence, future research unveiling the effect of apigenin on miR-194-3P will explain its mechanistic pathway in a better way

5 Treatment status and prospects IVDD is a leading cause of disability globally, imposing a substantial burden on both personal health and socioeconomic systems