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The surface electrostatic potential (lower panel) was calculated via PyMOL, and the positively charged regions potentially implicated in the interaction with DNA are denoted by black dashed lines

Excluded or Cautioned Populations in Phase 3 Trials Phase 3 REDEFINE/REIMAGINE protocols typically excluded participants with: Type 1 diabetes

It modulates macrophage function, stimulates antimicrobial peptide production, inhibits bacterial proliferation (203), and regulates CD4 + T cell responses

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