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Reported side effects in human anecdotal use are generally mild and may include: Mild nausea, particularly with oral administration Redness, itching, or irritation at the injection site Temporary dizziness or mild headache Changes in appetite or weight A significant theoretical concern revolves around its pro-angiogenic properties

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Chen J, Zhou Q, Wu Q, Yang J, Huang B, Mu W, Mei Q, Zhao H, Hu H, Liu F, Guo J, Zhao H (2026) Research progress on exogenous substances and their mechanisms of action in alleviating low-temperature stress in plants

52 The resulting loss of functional ATP7A in the intestine leads to reduced Cu efflux into the blood, an accumulation of Cu in enterocytes, and generalized severe systemic Cu deficiency