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If the same active substance shown in the figure above is given via another route, such as a tablet given orally (by mouth), the bioavailability is lower than 100% (see figure below, Oral bioavailability)

They also reported that feeding studies involving humans and consumption of isothiocyanate-rich cruciferous vegetables have demonstrated measurable Nrf2 activity, reflected in increased levels antioxidant proteins and enzymes, including glutathione S-transferase and NQO1

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"Additionally, serum and hepatic homocysteine levels could serve as a biomarker for NASH severity." Homocysteine may similarly affect other liver proteins, and finding out what they are is a future research direction for the team