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cl), 3- (N- (N ', N' -dimethylaminoethane) -carbamoyl) cholesterol (DC-Chol), N- (1, 2-dimyristoyloxyprop-3-yl) -N, N-dimethyl-N-hydroxyethylammonium bromide (DMRIE), 2, 3-dioleyloxy-N- [2 (spermine-carboxamido) ethyl ] -N, N-dimethyl-1-propanaminium trifluoroacetate (DOSPA), dioctadecylamidoglycyl spermine (DOGS), 1, 2-dioleoyl-sn-3-phosphoethanolamine (DOPE) which carries a positive charge at physiological pH but does not carry a positive charge at acidic pH), 3-dimethylamino-2- (cholest-5-en-3-beta-oxybutane -4-oxy) -1- (cis, cis-9, 12-octadecadienyloxy) propane (CLinDMA), 2- [5 '- (cholest-5-en-3 -oxy) -3' -oxapentyloxy) -3-dimethyl-1- (cis, cis-9 ', 1-2' -octadecadienyloxy) propane (CpLinDMA), N-dimethyl-3, 4-Dioleyloxybenzylamine (DMOBA), 1, 2-N, N '-dioleylcarbamoyl-3-dimethylaminopropane (DOcarbDAP), 1, 2-N, N' -dioleylcarbamoyl-3-dimethylaminopropane (DLincarbDAP), 1, 2-dioleylcarbamoyl-3-dimethylaminopropane (DLincCDAP) and mixtures thereof A compound (I) is provided