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BPC157 has shown no toxicity in animal studies, but human safety is uncertain

Ulanovskaya OA, Zuhl AM, Cravatt BF (2013) NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

Clones of stem cells were identified that exhibited increased methylation of the Wnt antagonist gene SFRP5 , and where the pattern of histone methylation had changed to resemble more closely that found in cancer cells