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2019 titled The Self-Medication Hypothesis of Substance Use Disorders: A Reconsideration and Recent Applications. published by Harvard Psychiatry, mental health disorders increase the likelihood of substance abuse as individuals attempt to alleviate their psychological distress through drug use

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Although MEGA-PRESS has been demonstrated to be an acceptable means of estimating brain glutamate, the technique was not specifically designed for this purpose, and the best means of estimating the excitatory component of the glutamatergic pool continues to be debated [52, 95, 96]

PMID: 41995456 J VirolNipah virus matrix protein promotes NF-B activation by targeting multiple signaling modulators