Dysbiosis of the gut microbiota can trigger systemic immune activation and influence the brain through both the circulatory system and the vagus nerve, thereby promoting neuroinflammation and aggravating seizure and depressive symptoms (Bravo et al., 2011
Immunohistochemical staining for oligodendrocyte lineage markers, such as Olig2, PDGF--Receptor (PDGFR), and NKX2.2, provide significant insights into the maturation and differentiation stages of oligodendrocyte precursor cells (OPCs)
Table 1 reveals a male predominance across both groups without a statistically significant difference among them ( 2 = 0.37, P = 0.543)
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