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Ketamine as a model of schizophrenia (as acute ketamine administration was associated with schizophrenia-like or psychotomimetic symptoms with large effect sizes, an increase in positive and negative symptoms [275,276]) might escape from the extraordinary complexity of extrapolation from animal models of mental disorders in general [277]

A deficiency can hinder how the brain processes information and how nerves communicate, leading to issues like speech delays, cognitive difficulties, and behavioral challenges

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