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In Han Chinese, HLA-DQA1 (Asp at position 160) independently correlates with ACPA-positive RA, underscoring HLA-II molecules role in antigen presentation ( HLA-DQB1 03:02 allele reduces ACPA-positive RA risk in Malaysians (OR = 0.85), likely via T-cell receptor signaling modulation (Tan et al., 2021)

V.DemchenkoO

If your patient is being initiated on warfarin for an acute bilateral pulmonary embolism, maybe youre a little bit more aggressive in your dosing than for atrial fibrillation, where the risk of a complication (aka stroke) happening in the next couple of days is pretty minimal

Our review further suggests the possibility of an otherwise clinically silent phenomena which may persist in patients with decompensated cirrhosis even despite appropriate antimicrobial prophylaxis following index spontaneous bacterial peritonitis