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(2022) reported JUN, an oncogenic transcription factor, as a regulator of glycolytic metabolism in AML, since it increases the expression of hexokinase I (HKI) and HKII, glucose phosphate isomerase (GPI), phosphofructo-1-kinase (PFKP), aldolase A (ALDOA), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), phosphoglycerate kinase (PGK1), enolase 1 (ENO1), and PKM

Although no clinical trials have demonstrated TCM-induced ferroptosis in patients with GC, there is pre-clinical evidence that some TCMs can attenuate the progression of GC by inducing ferroptosis

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