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Andero et al., 2012], a Wolfram syndrome rat model (Seppa et al., 2021), a Down syndrome mouse model (Stagni et al., 2017), and aged rats (Zeng et al., 2012)

Nrf2 plays an intriguing role as a cryoprotector by promoting the expression of genes that may also contribute to the development of melanoma and other malignancies (Moloney and Cotter, 2018