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This endogenous formation pathway explains why even consumption of fresh, unprocessed red meat increases fecal NOC levels in controlled feeding studies, an effect not observed with poultry or fish consumption (10)

Collectively, these findings highlight the potential of amino acids such as arginine, proline, glutamate, methionine, cysteine, glutamine, and BCAAs as novel biomarkers for IPF diagnosis, disease staging, and progression monitoring