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The efflux process promotes the entry of leucine and arginine, thereby activating the mTORC1 signaling pathway [54]

Simultaneously, the opening of the mitochondrial permeabilization transition pore (mPTP) releases pro-apoptotic factors (such as Cyt-c), triggering endothelial cell death

(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells