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The methyl B12 we use needs to be compounded by a compounding pharmacy and as a result, has a shorter shelf life

Contraindications Given the limited safety data, conservative contraindications would include pregnancy or plans to become pregnant, breastfeeding, age under 18, severe liver or kidney disease, and any condition requiring medications with unknown interaction potential

a NNMT inhibitor such as a cation of Formula I or IA, or otherwise disclosed herein one or more chemical entities e.g., nicotinamide riboside, nicotinamide mononucleotide one or more NNMT inhibitors (such as a cation of Formula I or IA, or otherwise disclosed herein) is contacted with a cell expressing NNMT concurrently with one or more chemical entities (e.g., nicotinamide riboside, nicotinamide mononucleotide) that increase intracellular NAD+ levels to provide muscular therapy

At 1st Optimal, our medical team uses comprehensive data from lab testslike DUTCH hormone panels and metabolic markersto determine the precise dosage and timing that will work best for you