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N Engl J Med (2012) 366(4):34859

Similar results were observed in another clinical study, in which depressed patients showed increased hsa-miR-342 and reduced hsa-miR-146a and hsa-miR-155 levels in peripheral blood mononuclear cells, with a positive correlation between hsa-miR-342 and TNF- levels ( In an experimental study, a chronic social stress animal model induced depressive-like behaviors in mice and significantly reduced miR-184-3p levels in the neurons of the PVN (Xu et al., 2024)

An important component of -glucans in Pleurotus sajor-caju helps to protect from oxidative stress and obesity in obese mice by the action mechanism of bioactive components, which involves in inhibition of adipocytes and lipolysis

The complementary mechanisms of amylin and GLP-1 pathways have generated significant scientific interest, with researchers exploring whether combined receptor activation produces synergistic improvements in weight and metabolic outcomes