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Another major limitation is the lack of standardized protocols for carotenoid intake or supplementation

Rao AR, Raghunath Reddy RL, Baskaran V, Sarada R, Ravishankar GA

[5] 2,3-Bisphosphoglycerate is found in high concentrations in human red blood cells, whereas in other cells, it is present only in trace amounts

2.4 Disruption of copper homeostasis by sepsis Sepsis is a systemic inflammatory response syndrome triggered by pathogen invasion, which can lead to multiple organ dysfunction