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hepatica (PDB ID 2WB9)

[ 40 ] GSH is neuroprotective and may play a role in preventing additional CNS lesions

Positive AMPA receptor modulation in the treatment of neuropsychiatric disorders: a long and winding road

Indeed, an ER-associated isoform of SKN-1, SKN-1A, is known to be a monitor of proteasome function and may modulate crosstalk between the ER and SKN-1 (Lehrbach et al., 2017) Activation of SKN-1 initiates a physiological trade off Titration of SKN-1 expression is important for the pro-longevity nature of this transcription factor