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But since peptide coupling agents are described as immune sensitizers, it stands to reason that the risk even if its small exists for everyone.18 Copper peptide uglies Anecdotal reports suggest that some people may experience worsened skin aging, instead of anti-aging, after using products with GHK-Cu, a rare concern dubbed copper peptide uglies. While this isnt necessarily a safety issue, it is a (again, rare) potential negative effect of using copper peptide products

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Lotenfoe RR, Christie J, Parsons A et al: Absence of neuropathic pelvic pain and favorable psychological profile in the surgical selection of patients with disabling interstitial cystitis

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