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Targeting mitochondrial oxidative stress with Mitoq reduces net formation and kidney disease in lupus-prone Mrl-Lpr mice

Experimental Animals The experiments were conducted in male albino Wistar rats (weighing 160180 g, aged 57 weeks) which were obtained from Biogen Laboratory Animal Facility, Bangalore

Compared with the Con group, the concentrations of plasma IL-1 (Figure 8A), TNF- (Figure 8B) and MDA (Figure 8C) were all significantly increased in the LMA, MMA and HMA groups with statistically significant differences