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doi:10.1016/j.jare.2024.04.029

Moreover, other groups reported that the Asp-248, Glu-25, Asn-127, and Asp-40 residues in SLC30A10 are required for its ability to export Mn when expressed in HeLa cells 91 , whereas the Mn transport activity of SLC30A10 with an Asn-43 mutation was similar to that of wild-type SLC30A10 when expressed in various cell types, including hepatic HepG2 cells, neuronal AF5 cells, HEK293 cells, and embryonic fibroblasts 92

Amedei, A

This takes place by the nucleophilic attack of the GSH sulfur atom on electrophilic substrates,decreasing their reactivity with cellular macromolecules and forming an important line of defence for cell components from reactive molecules [22]