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The problem is that the digestive process, particularly stomach acid and the enzyme gamma-glutamyltransferase present in the gut lumen, can cleave glutathione into its constituent amino acids (glutamate, cysteine, glycine) before it is absorbed intact

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Targeting the Intersection of Neuroinflammation, Innate Immunity, and Mitochondrial Dysfunction There is evidence that LRRK2 mutations contribute to immune alterations both in peripheral organs and the brain, although our understanding of the underlying mechanism is incomplete (Wallings et al., 2020)