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This trade-off may be reasonable for individuals with significant healing needs and appropriate risk tolerance, but it should be made consciously rather than by default

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A meta-analysis of studies investigating modafinil in PD, using dosages of 200400 mg as per prescribing information, demonstrated a reduction of subjective, but not objectively measured daytime sleepiness [188]

Even still, observational studies cant confirm whether low B12 levels cause weight gain or whether supplementation can protect against it