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Select studies have also reported high blood glutathione levels to be associated with greater health, especially in elderly individuals [9]

Sample collection All mice were intraperitoneally anesthetized with 1.25% avertin at the dose of 15 L/g body weight before being sacrificed

Consistent with the observation that GSNO in a great excess of CoA reduces PDHC inhibition, we also found that although a low concentration of SNO-CoA in the presence of NADH can cause substantial inhibition of PDHC, adding a larger amount of the NO donor PAPA NONOate on top made the overall inhibition weaker (Fig

Clin Biochem 2009;42:10821090