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reported that downregulated IIS increased tau phosphorylation, promoted GSK activation, and decreased insulin receptor substrate-1 (IRS1), phospho-Akt, drebrin, and postsynaptic density (PSD95) resulting in cognitive impairment in the HFD model [156]

The upper result, plus the evidence that the ratio of IL18R1/CXCR3 is six fold more in the ovary than in the tumor, supports that IL18R1 is surplus and CXCL10 can directly bind to IL18R1 (Supplementary Fig

Cosmetic copper peptide formulations typically contain GHK-Cu at very low concentrations (0.05-0.2%) in topical bases optimized for skin penetration