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This phenomenon, known as metabolic endotoxemia, has been linked to: Chronic inflammation Insulin resistance Obesity Metabolic syndrome In animal studies, even modest increases in circulating endotoxins have been shown to trigger inflammatory responses that interfere with metabolic regulation

and 4 is defined as hypertonic flexor and extensor muscles [3]

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SKIN HEALTH & WOUND HEALING Potential treatment for multiple dermatological conditions through modulation of skin inflammation