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CJC-1295 has reached phase 2 trials, but development was discontinued following a fatal myocardial infarction in a participant shortly after their 11th dose of CJC-1295 [8, 9]

Assefa, B., et al., Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes

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Antibodies derived from patients or clinical source were identified, formulated and administered via inhalation to target the receptor-binding domain (RBD) of the virus, thereby blocking its interaction with angiotensin-converting enzyme 2 (ACE2) receptors, which are widely spread on human epithelium 37,38,39,40,41,42,43,44